How To Treat Acne?
Zits, spots, pimples…call them what you will, they are the enemy of every teenager.
Eight out of 10 adolescents experience some degree of acne. Trying every antiseptic soap and lotion available, many spend hours squishing out blackheads and looking with horror on every new eruption.
However, teenagers don’t have a monopoly on acne. To their dismay many adults develop it for the first time in their 20s or 30s. Worse again, just when they thought they had left the ‘pimply youth’ stage behind them, many see acne breaking out again in their maturity.
Acne is mostly an inflammatory response to lesions inflicted to some of the cells lining the sebum ducts caused by sebum outbreaks or sebum hardenning inside the hair follicles, and comes before the proliferation of acne bacteria within blocked pores.
Skin consists of two thin layers — an outer layer called the epidermis and a deeper layer called the dermis. The dermis contains blood vessels and fibres which give the skin its elasticity.
The epidermis contains a hard protein called keratin, which helps protect the skin. Hairs are present everywhere on the skin’s surface apart from the soles of the feet, the palms of the hands and parts of the genitals. Each hair has a root and a shaft. Small glands called sebaceous glands near the root secrete a fatty substance called sebum, which also gives the skin a protective covering. It is this area of hair and sebaceous glands that is affected when acne develops. And the substances keratin and sebum are major players in the development of acne. Bacteria at the site of a blocked gland aggravates the condition.
Acne lesions show up in areas of the skin that have a lot of sebaceous glands, such as the face, centre of the chest, the back above the waistline, shoulders and the neck.
One primary cause of acne lesions is though to be that there is too much keratin produced at the exit of the hair shaft. This blocks the surface and doesn’t allow the sebum out. Too much sebum is also being produced. Consequently the sebum builds up underneath and a plug of keratin and sebum then forms. If the upper portion of this plug is at the surface it becomes dark in colour from pigment (melanin) produced by surrounding cells in the epidermis. The result is a blackhead. If the plug remains under the surface it is referred to as a whitehead.
Sebum continues to be produced under a blackhead or whitehead and because it has no means of escape it injures the cell lining the walls of the sebum canals and then they begin to swell and the sebum and pus eventually bursts into the dermis underneath.
Redness and inflammation then occur as your body's response to injury, and pus is formed. Occasionally, in severe cases the dermis reacts by trying to ‘wall off’ the sebum and acne cysts are formed during this process.
Acne treatment must address the repair of skin lesions first and also inflammation, blocked pores, and acne bacteria, and always aim to avert acne scarring.
Healing skin lesions is a complex and dynamic process that results in the restoration of anatomical continuity and function.
There are four basic responses that can occur following a lesion:
Normal repair (reestablished equilibrium), is the response where there is a re-established equilibrium between scar formation and scar remodeling.
Excessive healing (fibrosis and contractures), there is too much deposition of connective tissue that results in altered structure and thus loss of function.
Deficient healing (chronic ulcers) is the opposite of fibrosis; it exists when there is insufficient deposition of connective tissue matrix and the tissue is weakened and fragile to the point where it can bruise and bleed easily.
Skin Regeneration.
Gentle action of skin regeneration triggers and enzymes to minimize scars
BIOSKINCARE CREAM brings you the ONLY skin renewal product that incorporates natural skin renewal activators and biological enzymes that gently dissolve or "digest" the damaged or worn out cells while at the same time triggers the proliferation of fibroblasts that give rise to new connective tissues and hydrating molecules within the skin: new collagen and elastin cells and glycosaminoglycans and proteoglycans. The result is a coordinated biological regulation of the skin renewal process and thus healthy skin and advanced skin rejuvenation.
The beauty and genius of nature's most complete and balanced biological skin revival serum is that it works by creating an equivalent of a NON TRAUMA exfoliation which means that your skin will react to the messanger molecules and the enzymes that recognize and degrade damaged cells and non functional tissues by activating its own biological response modifiers thereby supporting your body's immune system and repair mechanisms to treat skin injuries (cuts, bruises, abrasions, acne lesions, scars, wounds, burns), dysfunctional tissues (keratosis, keloid and hypertrophic scars, excess dryness) and prevent over reactions that further destroy tissues and immune-mediated inflammatory skin disorders (inflammatory acne, rosacea, eczema and most dermatitis reactions).
And it will do so in an environment that has also been provided with all the molecule messengers that are necessary for a) the recognition of those cells and tissues that are damaged and need to be "digested" by the enzymes and b) an orchestrated regeneration or biosynthesis of new healthy tissues and with antioxidants that limit damage from free radical generation from the cells that participate in the immune system and create them to fight invading microbes.
When the enzymes "digest" or dissolve the topmost micron of skin (part of the outer layer that is no thicker than a sheet of paper, slowly and over a period of time) unlike all other such methods as glycolic acid peels, dermabrasion or laser resurfacing, there is no heat and blistering, so there is nothing to heal.
When you burn your skin, your body creates healing protein like collagen and elastin bands, pus, melanin, water, and antibodies (inflamm-aging) that rush to the aid of the trauma. In that case, there actually IS a burn to tend to...
However, during your BIOSKINCARE™ treatment, there is NOT any burn or trauma repair. The proteins that transport the repair elements to the epidermis and underlying stratum corneum are flooded with your own molecules and DNA. The new skin growth that is waiting to be exposed is not only smoother and tighter on its own, but it has just been soaked with those reparative proteins and water holding molecules that hydrated your skin and flooded to the surface to come to the aid of the 'NON TRAUMA EXFOLIATION'.
For hard, rough and old scars clinical trials have shown that the best results from chemical, physical exfoliation or laser treatments is achieved when the treatment is combined with SKIN REGENERATING ACTIVATORS. The reason is after the skin has been damaged by exfoliators it is IMPERATIVE that skin healing progresses at a quick pace.
Skin healing is a highly ordered systemic process that involves the coordinated regulation of cell proliferation and migration, and tissue remodeling .
Skin Exfoliation usually only involves removal of dead skin cells. BIOSKINCARE™ is unlike any other exfoliation treatment available today because BIOSKINCARE™ is the only system that gently exfoliates with ENZYMES & NATURAL SKIN RENEWAL ACTIVATORS that signal your system to get rid of damaged skin cells and target the cells that play the biggest role in keeping skin young, the fibroblasts, which are deep down in the mesoderm (middle layer) and stimulate them to reproduce all the structural components of healthy skin. And the whole process is coordinated at the pace needed to restore a healthy and beautiful skin naturally.
The Skin Renewal Activators are natural skin regenerating peptides and glycomolecules that signal your body to accelerate skin renewal . The same molecules are found in healthy human skin when it is wounded. They coordinate and regulate cell proliferation and migration and tissue remodeling. But as we age these regulatory growth factors slow down their activity and it is necessary to supply them topically to achieve the same skin renewal achieved by youngsters.
Reaching the fibroblasts
The point is enzymes help the peptides and glyco messengers to reach the fibroblasts. Skin is not fragile but admirably tough, more a barrier than a membrane. That's why the outer (and toughest) layer, the stratum corneum, is also called the horny layer. It's about ten microns thick -a lot in the dermatology world- and consists of layers of the same dead cells (corneocytes) that compose fingernails. The horny layer is often compared to a brick-and-mortar construction: The large cells of the epidermis are packed tightly together, while the small spaces between them are filled with fats (lipids). The design is foolproof: The corneocytes keep foreign material out, and the lipids make sure water stays in. The second layer (the epidermis) is about 80µm micrometres or microns thick. The third layer (the dermis) contains the capillaries and nerve endings and is several millimeters thick.
A micrometre is one-millionth of a metre - one-thousandth of a millimetre. One micron is about a tenth of the diameter of a droplet of mist or fog. It can be written in scientific notation as 1×10−6 m, meaning 1 / 1,000,000 m.
Yet it's on this hard ground that most products are meant to work. Most skin-care products focus on moisturizing the 'dead' layer of the skin, the 10 microns or so that require water so they don't feel dry, but that is not enough and in most cases it is deleterious for it ends wetting the skin too much.
The combination of tough stratum corneum layer and live epidermis makes it extremely difficult for external substances to penetrate skin. Traditionally, only small water-soluble molecules are able to diffuse slowly into the skin. Physical exfoliation of 10 or so microns, specially of rough scar tissues helps active ingredients to penetrate more easily the outer layer of the skin into the epidermis and the basal layer, while they also polish the surface and make it softer and look and feel more even. If scars are new and damage to skin is minor, or for routine exfoliation the action of the enzymes in BIO SKIN CLEAR or in BIO ACNE CARE is best. For rough, old and ice pick scars BIO SKIN EXFOL for microdermabrasion is best.
BIO ACNE CARE 
Gentle but effective acne treatment serum for pimples & acne cysts
The product is oil free and contains the following ingredients that act in concert to yield benefits that go beyond the sum of those of their specific parts:
a) our biological Helix Aspersa Müller Glycoconjugates with antioxidant, antimicrobial & skin regeneration properties to heal skin lesions within the follicles, control acne bacteria and prevent and get rid of acne scars;
b) the active extract of the bark of the Black willow ( Salix Nigra) tree to enhance cell renewal on the surface of the skin, unclog pores and reduce acneic skin flora (Propionibacterium acnes and Staphylococcus aureus). The actual content of willow (Salix Nigra) extract expressed as standarized salicylic acid is less than 0.5%. The Salix Nigra extract also provides natural B-hydroxy acid activity, without the skin irritation commonly associated with synthetic salicylic acid;
c) modified glucomannan (carbohydrate) -high molecular weight heterpolysaccharides made up of glucose and mannose derived from the Japanese Konjac tuber (root)- that reduce the surface tension of oil and facilitates its dispersion into droplets. These droplets get distributed evenly along the skin’s surface, minimizing their presence and oily feel;
d) Hyaluronic Acid a glycosaminoglycan (also present in the snail serum) to deeply moisturize the skin and restore the capacity of the skin to hold in moisture; and seaweed extracts that provide moisture and trace minerals necessary for the recovery of damaged skin cells; and sodium salt of pyroglutamic acid (naturally in human skin) moisturizer;
e) Japanese Licochalcone LR-15 from Licorice (Glycyrrhiza inflate) extract which clinicals (*) in Japan have shown that at very low concentration reduces undesired p. acnes and other acneic skin flora, is anti-irritating, anti-inflammatory and reduces sebum output.
Apply a thin layer twice a day on all the area affected with acne (whole face, chest or back) and then always use sun protection. If you are allergic to salycilic acid or to aspirin do not use the product and if you experience stinging or irritation (very unlikely) you must stop using the product and consult your physician.
Made in the USA. One Month Supply 50 grams = 1.76 oz
50 Grams in Airless Pump Bottle.
Regular Price: $54.98
For a limited time: $49.95
(*) A New Dermatological Availability of the Flavonoid Fraction from Licorice Roots-Effect on Acne
Journal of Society Cosmetic Chemists Japan, VOL.37; NO.3; PAGE. 179-186(2003) Authors: Kambara Toshimitsua, Zhou Y, Kawashima Yoshihitoa, Kishida Naokoa, Mizutani Kenjia, Ikeda Takaoa, Kameyama Koichirob.
a Research Center, Maruzen Pharmaceuticals Co., Ltd., 1089-8 Sagata, Shin-ichi, Fukuyama, 729-3102 Hiroshima, Japan. bAoyama Dermatological Clinic, dr@aoyamahihuka.com 5-1-3 Aoyama 8F Minato-ku Tokyo 107 Japan.
Abstract: Licochalcone-A, Polyol Soluble Licorice Extract P-U (now in the market as Licochalcone LR-15), prepared from the roots of Glycyrrhiza Inflata Batalin shows several activities such as inhibitory actions of testosterone 5 ALPHA-reductase, lipase and phospholipase A2, as well as androgen receptor antagonist, antimicrobial and SOD-like antioxidant actions, which relate to skin care, especially the suppression of acne formation and development. On basis of this evidence, a trial with acne patients was carried out and the efficacy of the extract was demonstrated clinically.
Ultra exfoliate rough scars and dull skin with BIOSKINEXFOL
Home microdermabrasion cream. Contains the same natural ingredients in BIOSKINCARE but infused with micro-crystals so that you may rub it with your finger tips to remove old, hard, and tough scars or Acne Scars by a physical breakdown of the scar tissues. Best also for oily skin and aged skin, actinic keratosis scales and pitted acne scars. Not for keloids and not if your skin is still fragile (use BIOSKINCARE for a few months first to strengthen your skin). The compounded action of the physical abrasion and the enzymes in the cream liquefy damaged proteins more thoroughly helping to release amino-acids to aid in rebuilding damaged tissues quickly. Results are not only immediate, but compound over time and do not trigger inflamm-aging of delicate skin tissues.
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Made in the USA. Two to Three Month's supply 120 grams = 4.23 oz
120 Gram Bottle: $79
Get rid of hiperpigmentation of scar areas and tissues and sun & age spots while reviving and protecting the skin from the effects of free radicals with BIO SKIN REJUVENATION
A deeply moisturizing natural skin care cream that replenishes the lipid barrier of the skin and triggers the repair of cells damaged by UV radiation and Free Radicals. Also gets rid of brown, sun and age spots, actinic keratosis scales and all types of skin blemishes. The same ingredients in BIOSKINCARE with an added natural substance that reduces melanin hyperpigmentation and a biomimetic peptide that inhibits the accumulation of melanin pigments.
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One Month's Supply 1.76 oz., 50 Gram Bottle: $69.98
The Biological Skin Treatment Complex
The biological activity in human skin of a complex carbohydrate and protein compound, collected from a live creature that produces it to regenerate its skin and organs when damaged, enhances the flow of information that is necessary to repair skin damage in an orderly, orchestrated way, with scarless healing.
The serum in our BIOCUTIS products has the unique ability to dissolve damaged and abnormal collagen protein fibers in the dermis where they were created to repair damaged tissues that may result when inflammatory reactions destroy our own tissues in their quest to protect us from invading bacteria or foreign materials. It does so through the action of "digestive" enzymes that breakdown proteins into their amino acid components in coordination with the glycomolecules in the compound that help to discern damaged cells from normal functional cells.
When the liquid active biological ingredient is combined with lipids (Olive Oil derivatives) to make it into a cream and micro-crystals are added to the final product, it accomplishes results for old and rough acne scars through a polishing or microdermabrasion action, while also hydrating deeply, strengthening cell membranes and triggering an orderly regeneration of the skin matrix.
We collect the rich biological ingredient by using a humanely method without harming any of the little creatures.
BIO ACNE CARE ™ 
A serum for moderate acne breakouts and for cystic acne. Contains the following ingredients acting in concert to yield benefits that go beyond the sum of those of the components:
a) Helix Aspersa Müller Glycoconjugates with antioxidant, antimicrobial & skin regeneration properties to heal skin lesions within the follicles, control acne bacteria and prevent and get rid of acne scars;
b) The active extract of the bark of the Black willow ( Salix Nigra) tree to enhance cell renewal on the surface of the skin, unclog pores and reduce acneic skin flora (Propionibacterium acnes and Staphylococcus aureus). The actual content of willow (Salix Nigra) extract expressed as standarized salicylic acid is less than 0.5%. The Salix Nigra extract also provides natural B-hydroxy acid activity, without the skin irritation commonly associated with synthetic salicylic acid;
c) Modified glucomannan (carbohydrate) -high molecular weight heterpolysaccharides made up of glucose and mannose derived from the Japanese Konjac tuber (root)- that reduce the surface tension of oil and facilitates its dispersion into droplets. These droplets get distributed evenly along the skin’s surface, minimizing their presence and oily feel;
d) Hyaluronic Acid a glycosaminoglycan (also present in the snail serum) to deeply moisturize the skin and restore the capacity of the skin to hold in moisture; and seaweed extracts that provide moisture and trace minerals necessary for the recovery of damaged skin cells; and sodium salt of pyroglutamic acid (naturally in human skin) moisturizer;
e) Licochalcone LR-15 from Licorice (Glycyrrhiza inflate) extract which clinicals in Japan have shown that at very low concentration reduces undesired p. acnes and other acneic skin flora, is anti-irritating, anti-inflammatory and reduces sebum output.
50 Grams in Airless Pump Bottle.
Regular Price: $54.98
For a limited time: $49.95
BIOSKINCLEAR ™ 
An oil free moisturizer gel for acne, rosacea and facial scars. Heals lesions to the cells lining the hair follicles which is the root cause of inflammatory acne. Removes dead cells, unclogs sebum canals and dissolves scar tissues by enzymatic hydrolysis, without peeling. Promotes the proliferation of antimicrobials that control acne bacteria. Boosts reproduction of glycosaminoglycans, the molecules that retain water, thus truly moisturizing the skin from within. Tells the body it is being taken care off and can moderate an otherwise extreme inflammatory reaction that may end up destroying healthy skin cells and creating crater like scarring and not only the acne bacteria.
50 gram (1.76 oz) airless pump bottle $49
25% off for two or more.
BIOSKINEXFOL™
A home microdermabrasion cream with micro-crystals that breakdown hard, rough and old scar tissues, and allow for a deeper penetration of the natural skin regeneration complex that is in the cream.
BIOSKINCARE ™ 
A natural skin care cream (without the micro-crystals) that triggers the regeneration of damaged cells and replenishes the lipid barrier of the skin while preventing and removing scars after healing of burns, injuries, wounds or surgery; Acne Scars; aberrant hypertrophic and keloid scars; keratois pilaris, actinic keratosis scales, dermatitis, dryness, cracked skin and all types of skin blemishes.
50 gram jar = $59.98
Two or more 20% discount
BIO SKIN REJUVENATION ™
Same cream base and enzymes as in BIOSKINCARE to "digest" or dissolve blemishes, speed skin turnover and tighten skin, and two added ingredients: one is a human growth factor peptide, derived from the melanocyte-stimulating-hormone. Blocks melanin synthesis, and reduces the formation of unwanted pigmentation, allowing control over skin tone and brown spots. The other is a natural plant extract that takes away dark pigmentation. Leaves skin bright and refreshed!


